39th Annual Meeting of the German Society for Microcirculation and Vascular Biology (GfMVB)

Peaks in Vascular Biology
5–7 October 2017 • Grainau / Garmisch-Partenkirchen, Germany

39th Annual Meeting of the German Society for Microcirculation and Vascular Biology (GfMVB)

Peaks in Vascular Biology
5–7 October 2017 • Grainau / Garmisch-Partenkirchen, Germany

Congress details

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Scientific programme

12.00 Registration
13.00 Opening Remarks
13.15-14.45 Session I: New insights in leukocyte trafficking
Chairs Markus Sperandio (Munich), Barbara Walzog (Munich)
13.15-15.35 How leukocytes trigger the opening of endothelial junctions. How leukocytes trigger the opening of endothelial junctions.
Dietmar Vestweber, Münster
13.35-15.55 Integrin signaling during neutrophil trafficking in innate immunity.
Barbara Walzog, Munich
13.55-14.15 The role of S100A8/A9 in neutrophil recruitment in vivo.
Monika Prünster, LMU MunichClaudia Nussbaum, Munich
14.15-14.30 Myosin 1f is specifically required for 3D migration of neutrophils during the inflammatory response. (Abstract 4)
Melanie Salvermoser, LMU Munich
14.15-14.30 LPS-induced maternal inflammation promotes fetal leukocyte. recruitment and death (Abstract 20)
Katinka Karenberg, Heidelberg
14.45-15.15 Coffee break
15.15-16.45 Session II: Frontiers in vascular inflammation
Chairs Hendrik Sager (Munich), Christian Weber (Munich)
15.15-15.35 Neutrophils in atherosclerosis - from initiation to destabilization.
Oliver Söhnlein (Munich)
15.35-15.55 circular RNAs in atherosclerosis.
Andreas Herbst, LMU Munich
15.55-16.15 Psychosocial stress and atherosclerosis.
Henrik Sager (Munich)
16.15-16.30 PreImplantation factor impairs leukocyte recruitment in vivo via influencing leukocyte adhesion and post-arrest modification. (Abstract 30)
Roland Immler, LMU Munich
16.15-16.30 The RhoGEF Trio induces junctional F-actin bundles by locally activating Rap1 to stabilize VE-cadherin-based cell-cell junctions. (Abstract 34)
Jaap van Buul, Amsterdam, Netherland
16.45-18.00 Coffee break & poster walk I
18.00-19.00 DZHK Keynote Lecture I
Chair Markus Sperandio (Munich)
Mother nature's box of vascular tricks as seen through a physiologist's eye.
Ulrich Pohl, LMU Munich
19.30 Dinner
08.00-09.00 Breakfast
09.00-10.30 (DZHK Session) Session III: non-coding RNAs in vascular biology (DZHK Session)
Chairs Rabea Hinkel, Stefan Engelhardt
09.00-09.20 lncRNA and circ RNA as miR sponges
Reinier Boon, Frankfurt
09.20-09.40 miRNA in restenosis
Lars Maegdefessel (Munich)
09.40-10.10 miRNA and platelet function
Ingrid Fleming (Frankfurt)
10.10-10.30 Cardioprotective Potential of miR92a Inhibition via LNA in a pig model of hibernating myocardium (Abstract 37)
Katharina Klett, TUM Munich
10.30-11.00 Coffee Break
11.00-12.30 Session IV: Immunology in transplant medicine
Chairs Bruno Reichart, Eckhard Wolf
11.00-11.20 Genetic modification for tayloring xenotransplantation donor pigs.
Nick Klymiuk, LMU Munich
11.20-11.40 tba. Elmar Jaeckel, MHH Hannover
11.40-12.00 Insights and successes in the field of xeno-heart-transplantation.
Bruno Reichart, LMU Munich
12.00-12.15 Inducible expression of Thymosin β4 via AAVs ameliorates ischemic damage in pig and rabbit models.
Tilman Ziegler, TUM Munich
12.30-15.00 Lunch, poster walk II
15.00-16.30 Session V: Young Investigator session
Chairs Florian Limbourg, Ferdinand LeNoble
15.00-15.15 Arterial Flt1 regulates de novo arteriologenesis and arteriolar caliber involving novel endothelial remodeling events (Abstract 7)
Alina Klems, KIT Karlsruhe
15.15-15.30 Targeting HDAC9 Limits NF-κB Signaling and Attenuates Experimental Atherosclerosis: Prospects for Pharmacological Intervention (Abstract 22)
Yaw Asare, LMU Munich
15.30-15.45 Annexin A1 induces a pro-angiogenic macrophage phenotype to promote myocardial repair (Abstract 26)
Bartolo Ferraro, LMU Munich
16.00-16.15 Coronary autoregulation is attenuated by a KATP channel dependent mechanism (Abstract 38)
Rainer Windler, Lübeck
16.15-16.30 Role of Lysozyme M+ cells in the development of angiotensin II-induced vascular inflammation (Abstract 39)
Johannes Wild, Mainz
16.30-17.00 Coffee break
17.00-17.45 Keynote Lecture II
Chair Christian Kupatt
  Pulmonary Hypertension - a case for vascular gene therapy
Roger Hajjar, New York, US
18.00-19.00 Keynote Lecture III
Chair Christian Kupatt
  The lympahtic system in the diseased heart
Paul Riley, Oxford, UK
19.30 Dinner
21.00 Social activity
08.00-09.00 Breakfast
09.00-10.30 DZHK Session VI: Microcirculation & Clinics
Chairs Karl Ludwig Laugwitz, Derk Frank
09.00-09.20 Novel insights in anticoagulation
Manuela Thienel, LMU Munich
09.20-09.40 Novel insights in ACS / microthrombosis
Michael Joner, DHM Munich
09.40-10.00 Novel insights in aortic stenosis
Derk Frank, Kiel
10.00-10.20 Novel insights in lipid treatment
Thorsten Kessler, DHM Munich
10.30-11.00 Coffee break
11.00-12.30 Hermann Rein Award session
Chairs Henning Morawitz, Christian Kupatt
11.00-11.30 Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment
Almudena Ortega-Gómez, LMU Munich
11.30-12.00 Aged neutrophils contribute to the first line of defense in the acute inflammatory response
Bernd Uhl, LMU Munich
12.00-12.30 Regulation of monocyte cell fate by blood vessels mediated by Notch signalling
Jaba Gamrekelashvili, MHH Hannover
12.30-13.00 Closing session
  Hermann Rein award, announcement of next meeting
Chairs Katrin Schröder, Eckhard Wolf, Reiner Boone, Lars Mägdefessel
002 New targets for renoprotection: vascular smooth muscle Kv7.1 channels?
Rudolf Schubert, Mannheim
003 Role of Ca2+ and RhoA-mediated force generation at intercellular junctions in histamine-induced endothelial barrier disruption
Daniela Kugelmann, LMU Munich
005 Uromodulin as a modulator of inflammation
Monika Prünster, LMU Munich
006 The Histone Demethylase Jarid1b regulates vessel tone by induction of vasoactive lipid-metabolites
Andrea Vasconez, Frankfurt am Main
007 Arterial Flt1 regulates de novo arteriologenesis and arteriolar caliber involving novel endothelial remodeling events.
Alina Klems, Karlsruhe
008 Long non-coding RNA S1PR1-AS is required for S1P signaling and endothelial cell function
Ivana Josipovic, Frankfurt am Main
009 Endothelial barrier regulation by cAMP: role of Epac1 and adducin
Mariya Radeva, LMU Munich
010 The AMP-activated protein kinase (AMPK) causes vasodilation by reducing calcium sensitivity and altering actin filament dynamics in microvascular smooth muscle
Jiehua Qui, LMU Munich
011 The Low Density Lipoprotein Receptor-Related Protein 1 is critical for Neutrophil Trafficking Mediated by the Cytokine Midkine
Ludwig Weckenbach, LMU Munich
012 Src Family Kinases are essential for neutrophil extravasation
Ina Rohwedder, LMU Munich
013 Mitochondrial Thioredoxin Reductase and its importance for vascular homeostasis
Christoph Nuernbergk, LMU Munich
014 A fundamental role of Myh9 for neutrophil trafficking in innate immunity
Annette Zehrer, LMU Munich
015 Characterization of novel Coronin 1A interacting partners: the zebrafish model as tool to study leukocyte recruitment
Daniela Begandt, LMU Munich
016 Role of Coronin1B on the Regulation of the Endothelial Function, Angiogenesis and Leukocyte Extravasation
Ann-Cathrin Werner, LMU Munich
017 CD40L dependent platelet string formation in the mouse microcirculation in vivo
Sibgha Tahir, LMU Munich
Chairs Ralf Brandes, Thorsten Kessler, Barbara Walzog, Markus Sperandio
018 Regional LNA-132 application inhibits miR-132 expression and prevents hypertrophy induced cardiomyopathy in pigs
Andrea Bähr, TUM Munich
019 SphK2-S1P Signaling is involved in Systemic and Vascular Inflammation during Experimental Hypertension
Anja Meissner, Lund, Sweden
021 Expression profile and role of acid sensing ion channels (ASICs) in modulating vasomotor response of cultured rat cerebral arteries to acidosis ASIC expression in cultured rat cerebral arteries and the role thereof in vasomotor response to acidosis Vascular inflammation by short term culture: effects on acid sensing ion channels (ASIC) expression profile and vasomotor responses in rat cerebral arteries
Lothar Schilling, Mannheim
023 Cross-talk between the nuclear factor endothelial 2 like 2 and the aryl hydrocarbon receptor via microRNA 125b in the response of endothelial cells to cigarette smoke exposure
Mohamad Musbah Almedawar, Dresden
024 Oxidized LDL, Angiotensin II and Oxidative Stress
Henning Morawitz, Dresden
025 Inhibition of farnesylation of Ras-GTPases ameliorates inflammation-induced loss of endothelial barrier integrity and leukocyte transmigration
Muhammad Aslam, Giessen
027 Danger mobilizes Neutrophils
Quinte Braster, LMU Munich
028 Chrono-pharmacological targeting of the CCL2-CCR2 axis ameliorates atherosclerosis
Carla Winter, LMU Munich
029 Left Ventricular Unloading using an Impella CP® Improves Coronary Flow and Infarct Zone Perfusion in Ischemic Heart Failure
Olympia Bikou, New York, US
031 S1P attenuates sepsis induced hypercirculation in LPS-stimulated mice
Farah Abdel Rahman, TUM Munich
032 Pericardial adipose tissue regulates granulopoiesis, cardiac fibrosis and function after myocardial infarction
Sabine Steffens, LMU Munich
033 A Self Assembling Split GFP Reporter System for Tracking in vivo Split Cas9 Activity
Tarik Bozoglu, TUM Munich
036 Septic hypercirculation mediated by the VEGF-Receptor adaptor protein TSAd
Murat Asadi, TUM Munich
040 Circulating CD172a+ cardiac microvesicles are a new biomarker of myocardial ischemic stress – Results from the in vivo porcine model and different cardiovascular disorders
Ruth Thalmann, TUM Munich
041 The amazing maze of (H)NO relaxation: activation of sGC and/or oxidation of PKG
Kjestine Schmidt, Lübeck
042 Association of the coronary artery disease risk gene GUCY1A3 with on-aspirin platelet reactivity and ischemic events after coronary interve
Berhard Wolf, DHM Munich